Bullous disorders are conditions where the body’s immune system targets skin-anchoring proteins, causing fragile skin and fluid-filled blisters on the body or inside the mouth. They’re not contagious, but they can be serious without specialist care. At Muthu Skin, Hair & Laser Clinic, our dermatologists provide rapid diagnosis, safe steroid protocols, and modern steroid-sparing therapies to induce remission and prevent complications.
Pemphigus vulgaris / foliaceus – fragile, easily breaking blisters; mouth and nose sores common (PV)
Bullous pemphigoid (BP) – tense, itchy blisters in older adults; may start as urticarial rash
Mucous membrane pemphigoid – mouth/eye/genital involvement; scarring risk (needs close follow-up)
Dermatitis herpetiformis (DH) – intensely itchy, grouped bumps/blisters; gluten-related association
Linear IgA disease – “string of pearls” blisters; Common in children and adults
Pemphigoid gestationis – pregnancy-associated blistering (obstetric coordination required)
Sudden widespread blisters, painful skin, or raw erosions
Mouth/eye/genital ulcers, trouble eating or vision symptoms
Fever, malaise, or signs of secondary infection (pus, foul odour)
New blisters in the elderly or in pregnancy
Use non-stick dressings; avoid adhesive tapes on fragile skin
Lukewarm baths, gentle cleansers; moisturise daily
Soft toothbrush; avoid spicy/acidic foods during oral flares
Report fever, spreading redness, or medication side-effects immediately
Bring a drug list. Some medicines can trigger/worsen disease (we will review)
Autoimmune diseases that cause fragile skin and fluid filled blisters on the body or mucosa such as mouth and eyes
No. They are autoimmune conditions and do not spread from person to person.
Pemphigus makes fragile blisters that break easily and often affects the mouth. Bullous pemphigoid causes tense itchy blisters and usually affects older adults.
If you have widespread blisters, mouth or eye ulcers, fever, or signs of infection such as pus or foul smell.
With a skin examination, a biopsy, and direct immunofluorescence testing. Blood tests for specific antibodies help with staging and follow up.
Topical or oral steroids to control flares, plus steroid sparing medicines such as azathioprine, mycophenolate, methotrexate, doxycycline with niacinamide, or dapsone after tests.
Yes when dosed and tapered correctly with monitoring. We add bone sugar, and blood pressure protection where needed.
Use non stick dressings, gentle baths, and daily moisturiser. Avoid adhesive tapes on fragile skin and report fever or spreading redness early.
We use numbing mouthwashes, soft diet advice, and infection control. Good oral hygiene and dental checks are important.
Ophthalmology co care is essential to prevent scarring and vision problems. Seek same day review for eye pain, redness, or light sensitivity.
No specific diet cures these diseases, but balanced nutrition helps healing. Stress can worsen flares, so sleep and stress management are useful.
Some medicines are safe and some are avoided. We coordinate closely with obstetrician to plan a safe regimen.
Initially every two to four weeks, then spaced out once stable. Antibody levels and skin checks guide tapering.
Yes. We see patients from Mogappair West, Mogappair East, Nolambur, Ayanambakkam, and Anna Nagar and can arrange coordinated care when needed.
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